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Objective:To investigate the clinical effect of voice training on the vocal function of patients with early vocal fold polyps. Methods:From May, 2016 to May, 2018, 80 patients with unilateral wide-based vocal fold polyps were randomly divided into control group (n = 40) and experimental group (n = 40). Both groups underwent voice hygiene education, and the experimental group accepted voice training, 40 minutes a week for twelve weeks in addition. They were evaluated with fiber laryngoscope, voice handicap index (VHI) and the computer phonatory detection before and after training. Results:Five in the control group and seven in the experimental group were dropped out. After training, the cure rate and the improvement rate of vocal fold polyps were significantly higher in the experimental group than in the control group (χ2 = 24.608, P < 0.001). The scores of VHI significantly improved in the experimental group (t/Z > 11.701, P < 0.05), and were better than those in the control group (t/Z > 7.027, P < 0.001). The scores of jitter, shimmer, and maximum phonation time improved (|t/Z| >5.012, P < 0.001) after training in the experimental group, and were better than those in the control group (t/Z > 4.596, P < 0.001). Conclusion:Voice training could improve the vocal function of patients with early vocal fold polyps, reduce hoarseness, and improve the voice quality.
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·AIM: To observe the pupil diameter in different environment on myopia control effect of orthokeratology. ·METHODS: The optometry, pupil diameter and eye axial length were examined in 70 patients aged 8- to 13-year-old with low and moderate myopia, whom then were given night wear lenses, and we measured the length of eye axis and pupil diameter before wearing lenses,6, 12 and 24mo after wearing. In two different light environment groups, each group took the average pupil diameter as the dividing and divided into two subgroups; the pupil diameter higher than the mean group (19 cases, 17 cases respectively), the pupil diameter lower than the mean group (16 case, 18 cases respectively). The paired t-test, independent sample t-test, repeated measures ANOVA and Pearson correlation analysis were adopted to analyze. ·RESULTS: Whether in darkroom or exposed to natural light, the axial length of pupils whose diameter was lower than the mean diameter increased faster than that above the average diameter of pupils (P<0. 01). The initial pupil diameter was significantly negatively correlated with the growth of the eye axis at the end of the 24-month follow-up (r=-0.4267,P<0.05;r=-0.4925, P<0.01). · CONCLUSION: The myopia controlling effect of orthokeratology under two different illumination conditions showed that the effect of myopia control in children with larger pupils is better than that in children with smaller pupils, which may be that the larger pupil makes the orthokeratology maintain stronger intervention on peripheral retina myopic defocus.
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@#Retinoblastoma(RB)is the most common intraocular malignant tumor in infants, the pathogenesis of which, is related to gene mutations. In order to improve the survival rate and eye-protection rate of RB patients, the therapeutic approaches have been constantly updated and developed, mainly including chemotherapy, radiation therapy, surgical treatment, physiotherapy, photochemotherapy, gene therapy at present. In this article, we mainly reviewed the progress of RB treatment.
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Objective To observe the effect of atorvastatin on intraabdominal fat and microalbuminuria (MAU) in patients with metabolic syndrome (MS). Methods Forty-four MS patients were divided into the atorvastatin group and the control group. Blood pressure and blood glucose were controlled in both groups, in addition, atorvastatin was administered to the patients in the atorvastatin group. Blood pressure, blood glucose, body weight, abdominal wall fat, intraabdominal fat and MAU were compared before and after 12 weeks’ treatment. Results Obvious decrease of the intraabdominal fat and MAU was found in the atorvastatin group compared with those before the treatment Intraabdominal fat: non-ACE1/ARB (41.76?3.61) mm vs (33.23?2.47) mm, P
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50% of that before treatment; (3)Normal control group( n =10). The urinary retinol binding protein(RBP) and N acetal D amino glucosidase(NAG)were measured by ELISA. The urinary osmosis, 24 h urinary protein excretion and serum creatinine (Cr) were measured. Results: (1) The urinary RBP[(0.54?0.19) mg/L], NAG[(112.84?42.82) U/L] and osmosis [(553.62?248.91) mmol/L] in PNS patients were significantly higher than normal control group ( P